Treatment with β-elemene combined with paclitaxel inhibits growth, migration, and invasion and induces apoptosis of ovarian cancer cells by activation of STAT-NF-κB pathway.

In conclusion, the data suggested that β-elemene+paclitaxel can inhibit ovarian cancer growth via down-regulation of the STAT3-NF-κB signaling pathway, which may be a potential therapeutic strategy for ovarian cancer therapy. PMID: 32401925 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32401925?dopt=Abstract

Source: Braz J Med Biol Res - May 14, 2020 Category: Research Authors: Xiaomeng F, Lei L, Jinghong A, Juan J, Qi Y, Dandan Y Tags: Braz J Med Biol Res Source Type: research