Computational prediction and characterisation of miRNAs and their pathway genes in human schistosomiasis caused by Schistosoma haematobium.

CONCLUSIONS miRNA pathway occurs in the S. haematobium, including endogenous miRNAs and miRNA pathway components, suggesting a role of this type of non-coding RNAs in gene regulation in the parasite. The results found in this work will open up a new avenue for studying miRNAs in the S. haematobium biology in helping to understand the mechanism of gene silencing in the human parasite Schistosome.
PMID: 32401998 [PubMed - as supplied by publisher]

Source: Memorias do Instituto Oswaldo Cruz - May 14, 2020 Category: Infectious Diseases Authors: Cardoso TCS, de Araújo CB, Portilho LG, Mendes LGA, Alves TC, Silva GC, Ribeiro THC, Gandolfi PE, Morais ER, do Amaral LR, Gomes MS Tags: Mem Inst Oswaldo Cruz Source Type: research