AlpinumisoflavoneTriggers GSDME-dependent Pyroptosis in EsophagealSquamousCell Carcinomas.

CONCLUSIONS: AIF inhibited ESCC growth in vitro and in vivo by triggering GSDME-mediated pyroptotic cell death, which is dependent on caspase-3 activation.
PMID: 32396690 [PubMed - as supplied by publisher]

Source: Anatomical Record - May 11, 2020 Category: Anatomy Authors: Zhang B, Zhu WY, Tian H, Zhang HR Tags: Anat Rec (Hoboken) Source Type: research