Application of α-Amino-β-fluorophosphonates in Construction of their Dipeptide Analogues
Synthesis DOI: 10.1055/s-0040-1707813 Herein, we present application of α-amino-β-fluorophosphonates for the construction of their dipeptide analogues. α-Amino-β-fluorophosphonates were prepared in a XtalFluor-E mediated deoxyfluorination of α-hydroxy-β-aminophosphonates. The reaction proceeds through an aziridinium ion formation, which was confirmed by the formation of a hexacoordinate phosphorus compound. Moreover, the absolute configuration of the obtained compounds was determined by X-ray analysis, which proved the stereochemistry. [...] © Georg Thieme Verlag Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Synthesis - Category: Chemistry Authors: Ka źmierczak, Marcin Dutkiewicz, Grzegorz Cytlak, Tomasz Tags: paper Source Type: research
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