Maternal soy protein isolate diet during lactation programmes to higher metabolic risk in adult male offspring.

Maternal soy protein isolate diet during lactation programmes to higher metabolic risk in adult male offspring. Int J Food Sci Nutr. 2020 May 12;:1-11 Authors: de Almeida Brasiel PG, Schuchter Ferreira M, Vieira AM, Sarto Figueiredo M, Cristina Lisboa P, Gaspar de Moura E, Cesar Ferraz Lopes F, de Aguiar AS, Luquetti Dutra SCP Abstract Soy consumption and its components, including its protein, are related to the beneficial effects of the lipid profile, decreased insulin resistance and glycaemia. However, the safety of the consumption of products containing phytoestrogens in critical stages of development has been questioned, since they may be associated with endocrine-metabolic dysfunctions in adult life. The purpose is to evaluate the effects of maternal dietary soy protein isolate (SPI) during lactation on the breast milk composition, body composition, lipid and glycaemic profiles, and thyroid hormones of dams and offspring at weaning (21 days) and in adulthood (150 days). Lactating rats were divided into casein control (C) and SPI diet groups. At 150 days, the SPI offspring presented lower body protein mass and total mineral content, higher serum FT4, insulin, TC and TG. Maternal consumption of SPI during lactation programmes the progeny to higher metabolic risk profile. PMID: 32393141 [PubMed - as supplied by publisher]
Source: International Journal of Food Sciences and Nutrition - Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research