Human closed and open apex premolar teeth express different toll ‐like receptor

ConclusionThe results of the present study suggested increased expression ofTLR2 andTLR4 by the maturation of the apex, which may be due to the presence of microorganisms in the normal or destructed dental pulp tissue. Thus, identifying the expression of TLRs molecules in dental pulp tissue helps to develop a deeper knowledge of the immune responses in the oral cavity.

Source: Molecular Genetics & Genomic Medicine - May 12, 2020 Category: Genetics & Stem Cells Authors: Reza Jafari, Razieh Karamzadeh, Faezeh Pesaran Hajabbas, Fereshteh Sayyadizadeh, Zahra Chekini, Samaneh Aghajanpour, Leila Shakeri, Kiumars Nazarimoghaddam, Reza Aflatoonian Tags: ORIGINAL ARTICLE Source Type: research