Interaction of thrombophilic SNPs in patients with unexplained infertility —multifactor dimensionality reduction (MDR) model analysis

ConclusionTheMTHFR C677T polymorphism was significantly associated with UI, with minor allele T being more frequent. Additionally, there was a significantly increased presence ofMTHFR C677T withFVL mutation in these patients. Therefore,MTHFR and its interaction withFVL should be recognized as contributing factors in the pathogenesis of infertility.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research