The opioid epidemic in pediatrics: a 2020 update
We describe the historical use of opioids and the scope of the current opioid crisis, review the differences between dependence and addiction, and the private and public sectors response to pain management and highlight the issue of adolescent vulnerability. We conclude with a proposal for future directions that address both public and patient health needs.
Publication date: December 2020Source: Tribology International, Volume 152Author(s): Chong Luo, Yi Xu, Nengyuan Zeng, Tengda Ma, Chenwei Wang, Yuling Liu
Publication date: Available online 2 August 2020Source: Journal of Membrane ScienceAuthor(s): Guang Yang, Zongli Xie, Aaron W. Thornton, Cara M. Doherty, Mingmei Ding, Hang Xu, Marlene Cran, Derrick Ng, Stephen Gray
This study included 250 subjects with NAFLD and 500 non-NAFLD controls. Clinical, anthropological and biochemical data were collected. Subjects with body mass index (BMI)>= 25 kg/m2 were taken as obese and subjects with BMI
Conclusion: Gastrointestinal side effects being most common side effect of metformin can lead to discontinuation of therapy. So before extensive evaluation of any GI problem in patient on metformin, other methods can be tried like temporary discontinuation, dose titration or proper intake of medicine. These side effects may also occur even after prolonged treatment with metformin. PMID: 32738838 [PubMed - as supplied by publisher]
Authors: Maydeo A, Patil G, Dalal A, Thakare S, Iyer A, Patil N Abstract Introduction: Endoscopic Sleeve gastroplasty (ESG) is a novel minimally invasive endoscopic restrictive bariatric procedure. We studied the safety, effectiveness, 6-month weight loss outcomes of ESG. Methods: We prospectively collected data for patients undergoing ESG at a tertiary care referral center. Laboratory investigations were performed preoperatively, and at 6 months post-operatively. Anthropometric measurements were noted pre and post-operatively at a frequency of 3 months for a 6-month follow-up. Patients with BMI ≥28 kg/m2 wh...
Esketamine nasal spray (Spravato), taken with an oral antidepressant, is now indicated in adults with major depression with acute suicidal ideation or behavior.Medscape Medical News
Publication date: Available online 3 August 2020Source: Food ControlAuthor(s): Siarhei Charapitsa, Svetlana Sytova, Anton Kavalenka, Lidia Sobolenko, Nikolai Kostyuk, Vladimir Egorov, Sergey Leschev, Sergey Vetokhin, Natalia Zayats
With all the news media accounts and reports from governmental health organizations about the opioid epidemic, including the 70,237 drug overdose deaths in 2017, a newly emerging threat is gaining attention: use and misuse of benzodiazepines, opioid drugs and Z-drugs. Specifically, combining these three drugs can create a deadly combination that snuffs out lives. Benzodiazepine Overdose Deaths on the Rise Benzodiazepines, a class of sedative narcotic drugs including Xanax and Valium used to treat anxiety, insomnia and other disorders and classified as Schedule IV under the Controlled Substances Act by the Drug Enforcement ...
Conclusion Evaluating the potential harms of a commonly used drug—especially a complex substance like marijuana—is a challenging but vital task. Fully informed awareness of both the potential and proven benefits and the potential and proven harms of marijuana are necessary in order to have rational discussions with patients, teens, and decision makers regarding marijuana use. Based on a review of the current literature, we suggest the mnemonic DDUMB (dependence, driving, underachievement, mental illness, and “bad to worse”) as a tool that captures several of the more well-supported, brain-based risk...
The prescription opioid crisis of overdosing and overprescribing has reached epic proportions, according to the North American media. Just last week, we learned that 91% of patients who survive opioid overdose are prescribed more opioids! The CDC calls it an epidemic, and notes there's been “a 200% increase in the rate of overdose deaths involving opioid pain relievers and heroin.” A recent paper in the Annual Review of Public Health labels it a “public health crisis” and proposes “interventions to address the epidemic of opioid addiction” (Kolodny et al., 2015).In the midst of this publ...
More News: Addiction | Alcoholism | Anesthesia | Anesthesiology | Child Abuse | Child Development | Children | Chronic Pain | Depression | Environmental Health | Epidemics | Epidemiology | History of Medicine | International Medicine & Public Health | Overdose | Pain | Pain Management | Pediatrics | Substance Abuse | Suicide | USA Health