APA Makes a Short Cut for Ramping up HSC Metabolism.

APA Makes a Short Cut for Ramping up HSC Metabolism. Cell Stem Cell. 2020 May 07;26(5):615-616 Authors: Jiang S Abstract The physiological role of alternative polyadenylation (APA) in controlling hematopoietic stem cell (HSC) behavior in vivo, and the mechanistic implications of this association, remain elusive. Now in Cell Stem Cell, Sommerkamp et al. (2020) provide evidence that APA regulates HSC self-renewal and multi-potency by affecting stem cell activation and glutaminolysis. PMID: 32386551 [PubMed - in process]
Source: Cell Stem Cell - Category: Stem Cells Authors: Tags: Cell Stem Cell Source Type: research