Matrine alleviates neurobehavioral alterations via modulation of JNK-mediated caspase-3 and BDNF/VEGF signaling in a mouse model of burn injury

ConclusionsThese findings provide convincing evidence that Mat improves anxiety- and depressive-like emotional status through modulation of JNK-mediated inflammatory, oxidative stress, apoptotic, and BDNF/VEGF signaling in an acute mouse model of burn injury.

http://link.springer.com/10.1007/s00213-020-05537-5

Source: Psychopharmacology - May 11, 2020 Category: Psychiatry Source Type: research