Analysis of soluble interleukin-2 receptor as CSF biomarker for neurosarcoidosis

Conclusions CSF sIL-2R parameters are elevated in patients with neurosarcoidosis, but this finding is not specific for neurosarcoidosis. Nevertheless, CSF sIL-2R parameters may help distinguishing neurosarcoidosis from MS and are associated with clinical, radiologic, and CSF disease activity markers of neurosarcoidosis. Classification of evidence This study provides Class II evidence that CSF sIL-2R parameters distinguish neurosarcoidosis from NINDs and MS.

http://nn.neurology.org/cgi/content/short/7/4/e725?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - May 10, 2020 Category: Neurology Authors: Otto, C., Wengert, O., Unterwalder, N., Meisel, C., Ruprecht, K. Tags: Article Source Type: research