An exceptional case of severe combined inherited thrombophilia successfully treated with rivaroxaban

We herein report the case of a young patient who presented with premature thromboembolic venous disease secondary to combined heterozygous G20210A prothrombin mutation, dual homozygosity for Factor V Leiden, and severe protein S deficiency. This association has never been reported to date and is likely to be exceptional, even in populations wherein these thrombophilia traits are more common. Long-term antithrombotic prophylaxis with rivaroxaban has proven successful in preventing clinical recurrence under prolonged treatment.

Source: Blood Coagulation and Fibrinolysis - May 11, 2020 Category: Hematology Tags: CASE REPORTS Source Type: research