Pencil beam scanning proton therapy for the treatment of craniopharyngioma complicated with radiation-induced cerebral vasculopathies: a dosimetric and linear energy transfer (LET) evaluation.
CONCLUSIONS: For children with and without RICVs, quantitative analysis showed a significant correlation with LETd average/maximum values in vascular structures, whilst no correlation was found on dosimetric parameters. PMID: 32387488 [PubMed - as supplied by publisher]
Conclusion. CP diagnosed in the elderly shows a similar distribut ion by sex and histologic forms than that diagnosed at younger ages. At presentation visual field alterations and headaches are the main clinical symptoms which improve substantially with surgery. However, surgery, mainly NTR, is accompanied by worsening of pituitary function, especially DI, which s eems to be a predictor of mortality in this population.
This case report describes a case of hemorrhagic papilledema in a man diagnosed with a craniopharyngioma.
CONCLUSIONS: Growth hormone treatment is a cause of pseudotumor cerebri syndrome. In our series, at risk patients had growth hormone deficiency and hypothalamic-pituitary anatomic anomalies or genetic or chromosome diseases. Fundus examination should be systematically screened in all patients in this at-risk group irrespective of the presence or not of symptoms. PMID: 33006547 [PubMed - as supplied by publisher]
In this study, we investigated whether immunohistochemistry could replace genetic analysis as an aid in subtype diagnosis. Here, 38 CP patients who had undergone their first tumor resection were included. Among the 38 cases, 22 were morphologically diagnosed as ACP, 10 cases were diagnosed as PCP, and six cases were diagnosed as undetermined CP that were morphologically difficult to classify as either ACP or PCP. Results of immunohistochemistry and genetic analysis and clinical features were compared. Based on the immunohistochemistry, 26 (22 ACPs and four undetermined CPs) showed nuclear β-catenin expression, 11 (nin...
Authors: Sprau A, Mahavadi A, Zhang M, Saste M, Deftos M, Singh H Abstract Background: Rathke's cleft cysts (RCCs) are benign, typically asymptomatic sellar lesions found incidentally in adults, with a dramatically lower incidence in pediatric patients (
To determine the preirradiation baseline association of white matter integrity with neurocognitive function and to assess posttreatment changes in pediatric patients with craniopharyngioma treated with proton therapy.
To determine the pre-irradiation baseline association of white matter integrity with neurocognitive function and to assess post-treatment changes in pediatric patients with craniopharyngioma treated with proton therapy.
AbstractSince there are many approaches for successful craniopharyngioma resection, how to choose a suitable approach remains problematic. The aim of this study was to summarize experience of approach selection and outcomes of craniopharyngioma resection in our institute. The data of 182 primary craniopharyngiomas between January 2013 and June 2019 were retrospectively reviewed. Craniopharyngiomas were classified into intrasellar, intra-suprasellar, suprasellar, and intra-third ventricle types based on the location. The surgical approaches, extent of resection, endocrine and ophthalmological outcomes, and complications wer...
Publication date: December 2020Source: Interdisciplinary Neurosurgery, Volume 22Author(s): Baha'eddin A. Muhsen, Bilal Ibrahim, Edinson Najera, Hamid Borghei-Razavi, Badih Adada