QT Interval Prolongation and Torsade De Pointes in Patients with COVID-19 treated with Hydroxychloroquine/Azithromycin

There is no known effective therapy for patients with COVID-19. Initial reports suggesting the potential benefit of Hydroxychloroquine/Azithromycin (HY/AZ) have resulted in massive adoption of this combination worldwide. However, while the true efficacy of this regimen is unknown, initial reports have raised concerns regarding the potential risk of QT prolongation and induction of torsade de pointes (TdP).

Source: Heart Rhythm - May 10, 2020 Category: Cardiology Authors: Ehud Chorin, Lalit Wadhwani, Silvia Magnani, Matthew Dai, Eric Shulman, Charles Nadeau-Routhier, Robert Knotts, Roi Bar-Cohen, Edward Kogan, Chirag Barbhaiya, Anthony Aizer, Douglas Holmes, Scott Bernstein, Michael Spinelli, David S. Park, Carugo Stefano, Source Type: research