Multivesicular Bodies (MVB) Mimicking SARS-CoV-2 in patients without COVID-19

It is now well known that patients with novel coronavirus disease (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) commonly have kidney complications, including acute kidney injury, proteinuria, and hematuria. Recent publications in this journal used electron microscopy (EM) to detect the virus in autopsy or biopsy specimens of the kidney1,2. Most of the published images depicting the suspected virus are very similar, if not identical, to MVB. MVB have been well-known since the 1960s and their appearance and occurrence is detailed in the classic monograph of Feroze Ghadially3; however, their exact significance and function is unclear.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: letters to the editor Source Type: research