Associations between reproductive factors and biliary tract cancers in women from the Biliary Tract Cancers Pooling Project

Our findings show that risk of gallbladder cancer (GBC) is increased among women who have given birth (especially women with 5 or more children). In women from Asian countries, later age at menarche increases the risk of GBC, intrahepatic bile duct cancer (IHBDC), extrahepatic bile duct cancer. We did not see this same association in women from Western countries. Age at menopause was not associated with the risk of any BTC.

Source: Journal of Hepatology - May 9, 2020 Category: Gastroenterology Authors: Sarah S. Jackson, Hans-Olov Adami, Gabriella Andreotti, Laura E. Beane-Freeman, Amy Berrington de Gonz ález, Julie E. Buring, Gary E. Fraser, Neal D. Freedman, Susan M. Gapstur, Gretchen Gierach, Graham G. Giles, Francine Grodstein, Patricia Hartge, Mazd Source Type: research