Endoscopic radiofrequency ablation plus a novel oral 5-fluorouracil compound versus radiofrequency ablation alone for unresectable extrahepatic cholangiocarcinoma

Endoscopic radiofrequency ablation (RFA) is a new ablative treatment for unresectable extrahepatic cholangiocarcinoma (EHCC). A novel 5-fluorouracil compound (S-1TM) has been widely used as one of the key drugs with first-line or second-line chemotherapy for the treatment of advanced cholangiocarcinoma. The aim of this study is to evaluate the clinical efficacy and safety of endoscopic RFA combined with S-1 for the treatment of unresectable locally advanced EHCC.

Source: Gastrointestinal Endoscopy - May 9, 2020 Category: Gastroenterology Authors: Jianfeng Yang, Jing Wang, Haibin Zhou, Yucheng Wang, Haitao Huang, Hangbin Jin, Qifeng Lou, Raj J. Shah, Xiaofeng Zhang Source Type: research