Thrombocytopenia During Prostacyclin Analogue Therapies of Pulmonary Arterial Hypertension—Possible Pathomechanisms and Implications

Abstract: Pulmonary arterial hypertension is a quite rare, but problematic disease in everyday cardiologists' practice. Prostanoids are the most important group of drugs used in this disease. One of the biggest problems encountered during treatment with analogs of prostacyclin is thrombocytopenia. Based on hematological guidelines we suggest common therapeutic schemes depending on the number of platelets or the severity of bleeding conducting the therapy.
Source: Journal of Cardiovascular Pharmacology - Category: Cardiology Tags: Drugs in the Pipeline – Review Article Source Type: research