[Pregnane X receptor promotes programmed cell death protein 4 expression in HepG2 cells].
CONCLUSIONS: Our findings demonstrate that PXR agonism in HepG2 cells increases the expression of PDCD4, which is independent of miRNA21 pathway, and PDCD4 may be a target gene of PXR in HepG2 cells.
PMID: 32376574 [PubMed - in process]
Source: Journal of Southern Medical University - Category: Universities & Medical Training Authors: Wang S, Li T, Du J, Han M, Ju D Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research