[Liquid chromatography tandem mass spectrometry for therapeutic drug monitoring of voriconazole in heat-inactivated blood samples: its application during COVID-19 pandemic].

CONCLUSIONS: Heat inactivation at 56 ℃ for 30 min combined with ethanol sample preparation only has limited effects to affect LC-MS-based voriconazole concentration measurement in whole blood samples collected in heparinized tubes, and can be used for therapeutic drug monitoring of voriconazole during the ongoing COVID-19 pandemic.
PMID: 32376593 [PubMed - in process]

Source: Journal of Southern Medical University - March 29, 2020 Category: Universities & Medical Training Authors: Zhao B, Liu S, Liu Y, Li G, Zhang Q Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research