RHB-105 Effective for Eradication of Helicobacter pylori in Adults

THURSDAY, May 7, 2020 -- A novel rifabutin-based triple therapy (RHB-105) is effective for eradication of Helicobacter pylori, with eradication rates unaffected by resistance to clarithromycin or metronidazole, according to a study published online...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Authors: Cáceres-Perkins W, Cabanillas F, San Vicente G, Rivera-Franceschini C, Sobrino-Najul E, Vega-Vázquez LI, Conde-Sterling D Abstract Mucosa-associated lymphoid tissue (MALT) lymphomas are B-cell neoplasms that commonly affect the gastrointestinal (GI) tract, usually the stomach. In most cases, extranodal marginal zone lymphoma (ENMZL) is an indolent disease. Bone marrow involvement is common with MALT lymphoma accompanied by paraproteinemia; such involvement impels disease progression. Here, we present the case of an 82-year-old Hispanic patient with long-standing ENMZL in whom the gastric site...
Source: Puerto Rico Health Sciences Journal - Category: International Medicine & Public Health Tags: P R Health Sci J Source Type: research
Publication date: Available online 8 October 2020Source: Materials Today: ProceedingsAuthor(s): Gattu Sampath, Douglas J.H. Shyu, Neelamegam Rameshkumar, Muthukalingan Krishnan, Nagarajan Kayalvizhi
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
Rationale: Dieulafoy lesion (DL), a rare cause of gastrointestinal bleeding, is easily covered by blood scab formation on the mucous membrane for its small size, which makes it difficult to be identified under endoscope. In clinical practice, it is also very easy to miss gastric mucosa-associated lymphoid tissue (MALT) lymphoma that exhibits atypical early manifestations under gastroendoscope and is difficult to be diagnosed by routine superficial biopsy. Most patients only experience nonspecific dyspepsia symptoms. Patient concerns: A 68-year-old man suffering from repeated melena for 6 years arrived at our hospital....
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Volume 12, Issue 1, November 2020, Page 1-12 .
Source: Gut Microbes - Category: Microbiology Authors: Source Type: research
10 ‐day amoxicillin–clarithromycin‐containing bismuth quadruple therapy may be recommended for the primary empirical treatment of Helicobacter pylori infection in China. The 14‐day therapy is expensive, uncomfortable for the patients, and has an increased risk of side effects. The 10‐day ther apy was not inferior to the 14‐day therapy in terms of efficacy. AbstractThe treatment regimen for the eradication ofHelicobacter pylori may be best when therapy is susceptibility guided. However, it is unrealistic to use a strategy based on susceptibility testing to prioritize therapy for every patient in China. Empir...
Source: MicrobiologyOpen - Category: Microbiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
In this study, we sequenced the 16S rRNA and 18S rRNA genes of fecal bacteria and fungi, respectively, in 134 gastric cancer patients and 58 healthy controls matched by age and gender. Propensity score matching (PSM) was adopted for adjusting diet habits and lifestyle, and 44 patients and 44 healthy controls (matching population) were enrolled. Serum antibody to H. pylori and metabolites of the matching population were detected. The positive rates of antibody to H. pylori between the patients and the control group did not reach the statistical difference. LEfSe analysis indicated that bacteria were more stable than fungi w...
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
Conclusions Despite the high prevalence of alarm symptoms at diagnosis, coincident major UGI endoscopic findings are rare in adult coeliac disease. These results may be relevant for future developments in coeliac disease diagnosis in adults.
Source: European Journal of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.0c04367
Source: Journal of Agricultural and Food Chemistry - Category: Food Science Authors: Source Type: research
Helicobacter pylori (H. pylori) is a gram-negative bacterium that chronically infects approximately 50% of the world ’s human population. While in most cases the infection remains asymptomatic, 10% of infected ind...
Source: Cell Communication and Signaling - Category: Molecular Biology Authors: Tags: Research Source Type: research
This study confirms previous reports of increased duodenal intraepithelial lymphocytes in patients with concurrentHelicobacter pylori gastritis. Intraepithelial lymphocyte counts of>  15 per villus or>  10 per 100 enterocytes were predictive of infection. Duodenal lymphocytosis decreases significantly after successful eradication therapy but remains elevated when treatment fails.
Source: Virchows Archiv - Category: Pathology Source Type: research
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