Increased Intravenous N-Acetylcysteine Dosing Following Massive Acetaminophen Ingestion: A Case Report

A young woman weighing 135  kg and with a medical history significant for depression presented to the emergency department after a suicide attempt with acetaminophen (APAP). The patient had been found unresponsive next to a bottle of immediate-release APAP, diphenhydrAMINE, and ibuprofen and had a Glasgow Coma Score of 3. Th e estimated APAP intake was 125 g 1 hour before the emergency medical services arrived. In the emergency department, the patient was intubated owing to altered mental status and lack of a gag reflex.
Source: Journal of Emergency Nursing: JEN - Category: Nursing Authors: Tags: Case Review Source Type: research