The Baltimore Bioterrorism Expert Who Inspired South Korea ’s COVID-19 Response
On Oct. 2, 2001, a 62-year-old photojournalist named Bob Stevens became the first victim of a coordinated series of anthrax attacks to be admitted to hospital. Stevens inhaled the deadly pathogen after opening one of several letters laced with anthrax spores which were mailed to the offices of prominent senators and media outlets across the U.S. Over the next seven weeks, he and four others would die as a result of their exposure. For a shell-shocked nation still reeling from the single deadliest terrorist attack in human history on September 11, it was a disturbing realization that there was a new wave of challenges to American security. In early 2002, President George W. Bush announced $11 billion worth of funding to tackle bioterrorism, initiating a decade-long program to establish action plans for how major cities like New York and Boston would cope in the event of a mass attack. But little did they know that nearly 20 years later, their plans for combating such a hypothetical attack would be utilized on the other side of the globe, inspiring an entire nation’s response to a very different infectious disease outbreak. After all back in 2001, few Americans had heard of bat-borne coronaviruses, least of all Sid Baccam, the Baltimore-based epidemiologist whose ideas for handling an anthrax attack would later be applied by a team of South Korean doctors racing to find a way to control a COVID-19 outbreak that was rapidly spiraling out of control. In the decade followin...
Publication date: Available online 10 July 2020Source: Clinica Chimica ActaAuthor(s): Xingzhong Hu, Dong Chen, Lianpeng Wu, Guiqing He, Wei Ye
Publication date: Available online 9 July 2020Source: Obesity Research &Clinical PracticeAuthor(s): Abdulzahra Hussain, Kamal Mahawar, Zefeng Xia, Wah Yang, Shamsi EL-Hasani
Publication date: Available online 10 July 2020Source: The Annals of Thoracic SurgeryAuthor(s): Andrea Marudi, Giacomo Branchetti, Elisabetta Bertellini
Publication date: Available online 9 July 2020Source: The Annals of Thoracic SurgeryAuthor(s): Gianluca Folesani, Luca Botta, Davide Pacini
Publication date: Available online 10 July 2020Source: Antiviral ResearchAuthor(s): So Young Kim, Weihua Jin, Amika Sood, David W. Montgomery, Oliver C. Grant, Mark M. Fuster, Li Fu, Jonathan S. Dordick, Robert J. Woods, Fuming Zhang, Robert J. Linhardt
Publication date: October 2020Source: Current Opinion in Virology, Volume 44Author(s): Yumiko Komatsu, Keizo Tomonaga
This report provides basic genetic data on genotype D11 for further study of me asles evolution and the support for measles elimination.
AbstractFeline morbillivirus (FeMV) is an emerging member of the familyParamyxoviridae that is suspected to be involved in chronic kidney disease (CKD). FeMV was first discovered in Hong Kong in 2012 and has subsequently been detected in many countries. However, the prevalence of FeMV in mainland China is still unclear. To clarify the present status and examine the genetic diversity of FeMV in mainland China, in this study, we collected cat urine samples in veterinary hospitals in Guangdong Province in 2017 and 2018. Using reverse transcription (RT)-PCR, we found that the urine of six out of 64 cats tested positive for FeM...
The objective of this study was to develop and validate a real-time quantitative PCR (RT-qPCR) protocol for the diagnosis of COCV directly from epithelial samples. The method developed had 97% accuracy at 3950 pfu and a repeatability error of 1.29%. RT-qPCR was able to distinguish COCV from other viruses that cause vesicular diseases, an important factor because seroneutralization may produce cross-reactivity between COCV and vesicular stomatitis Alagoas virus (VSAV). No epithelial sample originating from vesicular disease outbreaks between 2014 and 2018 in Brazil was positive for COCV.
In this report we describe the genotype constellation of a bovine rotavirus A (RVA) strain with an uncommon G8P genotype combination. The RVA/Cow-wt/BRA/Y136/2017/G8P strain was classified as G8-P-I2-R5-C2-M2-A3-N2-T9-E2-H3. Phylogenetic analysis based on the VP7 gene showed that the Y136 strain and a human G8P strain comprise a putative new (VII) lineage for the G8 genotype. In addition, two other genotypes, R5 (VP1) and T9 (NSP3), were identified in the constellation of Y136 that are rarely found in RVA strains of bovine origin. The immunological pressure caused by regular vaccination of cows might be resp...
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