Can this Asian medicinal plant be the key for treating depression? What you need to know about kratom

(Natural News) People suffering from depression and other mental and mood disorders may want to take a closer look at the kratom plant. Kratom (Mitragyna speciosa) is a tropical evergreen native to Southeast Asia, where it’s used as a herbal remedy for conditions like coughing, chronic pain, diarrhea and fatigue. The plant is best known — especially...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Conclusions: CLL imposes a significant HRQoL and economic burden. Our systematic review shows that an unmet need persists in CLL for treatments that delay progression while minimizing AEs. Studies suggest targeted therapies may reduce the economic burden of CLL but longer follow-up data are needed. PMID: 32634056 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
DiscussionThis randomized controlled trial will evaluate the effectiveness and safety of ESWT in patients with PHN and thus will provide clinical evidence for its use in the management of PHN and explore the potential biochemical mechanisms of this treatment.Trial registrationwww.ChiCTR.org.cn, identifier: ChiCTR1900025828. Registered on 10 September 2019
Source: Trials - Category: Research Source Type: clinical trials
  Lockdown is a “prison like” experience, for Londoner Annabelle Ume, who suffers from myalgic encephalomyelitis. “It’s very similar to being trapped in a bunker with no access outside,” says Ume.   Many other fellow sufferers are enduring pandemic enforced isolation without much hope. “They are staying in limbo until help is available and adapting to the worsening of their health conditions,” says Ume. “You just try to make mental peace with it because the physical can’t be addressed at this time.” COPD sufferer John Linnell from Wisconsin i...
Source: EyeForPharma - Category: Pharmaceuticals Authors: Source Type: news
In conclusion, LIN-NC is a promising proposal in the development of phytotherapy-based nanoformulations for future clinical applications. PMID: 32632735 [PubMed - in process]
Source: AAPS PharmSciTech - Category: Drugs & Pharmacology Authors: Tags: AAPS PharmSciTech Source Type: research
Abstract Chronic pain and depression are conditions that are highly comorbid and present with overlapping clinical presentations and common pathological biological pathways in neuroinflammation, both of which can be reversed by the use of electroacupuncture (EA) and omega-3 polyunsaturated fatty acids (PUFAs). Transient receptor potential V1 (TRPV1), a Ca2+ permeable ion channel that can be activated by inflammation, is reported to be involved in the development of chronic pain and depression. Here, we investigated the role of TRPV1 and its related pathways in the murine models of cold stress-induced nociception a...
Source: Brain, Behavior, and Immunity - Category: Neurology Authors: Tags: Brain Behav Immun Source Type: research
CONCLUSION: rTMS for patients with CP/CPPS seemed to be well tolerated, at least moderately effective in pain reduction, and might be of interest in patients with chronic pelvic pain resistant to conventional treatment. These findings remain to be confirmed by a randomized trial. PMID: 32615676 [PubMed]
Source: International Neurourology Journal - Category: Urology & Nephrology Tags: Int Neurourol J Source Type: research
Chronic pain is a complex experience that has now become a major public health issue. This has prompted many researchers to study attention, understanding it to be a crucial factor that allows altering the experience of pain, while attributing considerable...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
This study indicates that a MMR program could be beneficial for patients with subacute to chronic WAD, at least for women, since the outcomes at one-year follow-up were positive.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
In conclusion, physical exercise performed in water has positive effects on several factors that contribute towards improving the mood and quality of life of people with acquired brain injury.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Jeffrey A. SingerWhite House “drug czar” Jim Carroll toldPolitico earlier this week that an Office of National Drug Control Policy analysis finds an 11.4 percent year ‐​over‐​year increase in opioid‐​related overdose deaths during the first four months of 2020. Kentucky has seen a 25 percent increase in overdose deaths during the first four months of this year, and West Virginia saw a 50 percent increase in deaths since the beginning of the year. The data are incomplete at this point, and not all states have reported in.Mr. Carroll attributed much of the increase in the overdose rate ...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
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