Molecular analysis of lipid uptake- and necroptosis-associated factor expression in vitrified-warmed mouse oocytes.

CONCLUSIONS: We report that oocytes from aged mice show differential expression of CD36, which suggests that CD36-mediated lipid uptake may be influenced by age. We also show for the first time that pMLKL and pRIPK1 exhibit unique localization pattern in mouse oocytes and this may suggest role(s) for these factors in non-necroptosis-associated cellular processes.
PMID: 32366306 [PubMed - in process]

Source: Reproductive Biology - May 3, 2020 Category: Reproduction Medicine Authors: Um DE, Shin H, Park D, Ahn JM, Kim J, Song H, Lim HJ Tags: Reprod Biol Endocrinol Source Type: research