Benzyl alcohol accelerates recovery from Achilles tendon injury, potentially via TGF- β1/Smad2/3 pathway

Benzyl alcohol (BnOH), an aromatic alcohol produced by plants, is frequently used as a bacteriostatic preservative at 5% concentration in the treatment of head lice [1]. It is also used as an alternative local anesthetic [2] and attenuates acetaminophen-induced acute liver injury [3]. Research on the use of BnOH in wound healing is scarce, although its derivatives are widely used in wound healing. Benzoyl alcohol together with glycyl-1-histidyl-1-lysine copper complex was shown to increase wound healing and skin re-epithelialization, although benzoyl alcohol was known to inhibit the function of wound fibroblasts.
Source: Injury - Category: Orthopaedics Authors: Source Type: research