Prazosin for treatment of post-traumatic stress disorder: a systematic review and meta-analysis.

CONCLUSIONS.: Despite the results of a recent, large randomized study, pooled effect estimates show that prazosin has a statistically significant benefit on PTSD symptoms and sleep disturbances. Limitations that should be considered include heterogeneity of study design and study populations as well as the small number of studies conducted and included in this meta-analysis.
PMID: 32362287 [PubMed - as supplied by publisher]

Source: CNS Spectrums - May 3, 2020 Category: Neurology Authors: Reist C, Streja E, Tang CC, Shapiro B, Mintz J, Hollifield M Tags: CNS Spectr Source Type: research