Old age-associated enrichment of peripheral T regulatory cells and altered redox status in pulmonary tuberculosis patients.

CONCLUSIONS: We report old age-associated enrichment of Treg cells and suppression of M. tuberculosis-specific effector T (Th1) cell immune responses. Monitoring these immune imbalances in older patients may assist in immune potentiation through selectively targeting Treg cells and/or optimizing redox status by NAC supplementation. This article is protected by copyright. All rights reserved.
PMID: 32365223 [PubMed - as supplied by publisher]

Source: European Journal of Immunology - May 3, 2020 Category: Allergy & Immunology Authors: Namdeo M, Kandel R, Thakur PK, Mohan A, Dey AB, Mitra DK Tags: Eur J Immunol Source Type: research