High-scatter lymphocytes in the blood of erythrodermic cutaneous T cell lymphoma: evidence for large cell transformation?

Increasing number of large cells in the peripheral blood of E-CTCL patients may reflect large cell transformation. Using flow cytometry can accurately detect large cell population in E-CTCL patients (10 of 19 patients with SS, 1 of 13 patients with E-MF, and no patient with non-neoplastic conditions). Presence of HSLs connotes a poor prognosis even for patients with advanced disease.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Tags: Original Study Source Type: research