Update on disease pathogenesis, diagnosis, and management of primary Sj ögren’s syndrome

AbstractPrimary Sj ögren's syndrome (pSS) is a typical multisystem disease, characterized by lymphocytic infiltration of the exocrine glands leading to glandular dysfunction. Multiple systemic manifestations occur in those of serious conditions, with different courses and outcomes. Its pathogenesis is complex, and i ts diagnosis and management are being constantly updated and improved. We have failed to have much progress in targeted immunotherapy for pSS, and as yet this is still based on empirical treatment. Many studies have tried to define pSS more accurately, to study its pathogenesis, to find effective t reatment strategies, opening up new avenues for early diagnosis and precise management of pSS.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: REVIEW ARTICLE Source Type: research