Pattern of InhA and KatG mutations in isoniazid monoresistant Mycobacterium tuberculosis isolates

Conclusion: Knowledge about mutation patterns of different INH resistant strains is important in the present era where there is a provision of separate regimens for INH monoresistant TB. Since these mutations are very closely related to high- or low-degree resistance to INH, the therapeutic regimens cannot be generalized.

Source: Lung India - May 3, 2020 Category: Respiratory Medicine Authors: Ashok Singh Charan Neeraj Gupta Ramakant Dixit Piyush Arora Tarun Patni Kalliath Antony Manisha Singh Source Type: research