Cerebral blood flow velocity and oxygenation correlate predominantly with right ventricular function in cooled neonates with moderate-severe hypoxic-ischemic encephalopathy

Conclusion: CBF velocity and brain oxygenation correlate predominantly with RV function in HIE  + TH. This suggests a preferential contribution of RV performance to cerebral hemodynamics in this context.What is Known:• Neonates with hypoxic ischemic encephalopathy frequently exhibit alterations of cardiac function and cerebral blood flow.• These are considered organ-specific consequences of perinatal asphyxia.What is New:• We show that cerebral blood flow velocity and brain oxygenation are correlated predominantly with right ventricular function during therapeutic hypothermia.• This suggests a potential direct contribution of right ventricular performance to cerebral hemodynamics in this context.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research