Clinical implications of DLL4 expression in gastric cancer.

CONCLUSIONS: Cancerous and stromal DLL4 expression was found in 48% and 22% in gastric cancer, and significantly affected postoperative clinical outcomes. Cancerous and stromal DLL4 expression may be an effective target of anti-DLL4 treatment in gastric cancer.
PMID: 23898884 [PubMed - indexed for MEDLINE]

Source: Clinical Breast Cancer - December 22, 2013 Category: Cancer & Oncology Authors: Ishigami S, Arigami T, Uenosono Y, Okumura H, Kurahara H, Uchikado Y, Setoyama T, Kita Y, Kijima Y, Nishizono Y, Nakajo A, Owaki T, Ueno S, Natsugoe S Tags: J Exp Clin Cancer Res Source Type: research