Comprehensive analysis of hepatitis B virus infections in blood donors in southern China that are surface antigen positive but nucleic acid testing negative.

CONCLUSION: Fewer than half of HBsAg ELISA-positive/NAT-negative samples were confirmed as HBsAg positive. Our study demonstrates that in highly HBV-endemic countries, assays with high sensitivity and specificity may be required.
PMID: 32358842 [PubMed - as supplied by publisher]

Source: Transfusion - April 30, 2020 Category: Hematology Authors: Ye X, Li T, Zhang R, Liu H, Zeng J, Hong W, Lu L, Zhu W, Li S, Xu M, Wu S, Chen L Tags: Transfusion Source Type: research