Diagnostic accuracy of serum alpha-fetoprotein levels in diagnosing recurrent sacrococcygeal teratoma: A systematic review

The incidence of children developing recurrent sacrococcygeal teratoma (SCT) is 2 –35%. Serum alpha-fetoprotein (AFP) is often used as a tumor marker for (malignant) recurrences of SCT and could potentially be used during routine follow-up after SCT resection. However, the diagnostic accuracy of serum AFP levels during follow-up has not been well established. Therefore, we aime d to systematically review the diagnostic accuracy of serum AFP levels in recurrent SCT.

Source: Journal of Pediatric Surgery - May 2, 2020 Category: Surgery Authors: L.J. van Heurn, M.M. Knipscheer, J.P.M. Derikx, L.W.E. van Heurn Source Type: research