Multidisciplinary difficult airway challenges: Perioperative management of glottic and supraglottic tumours

Carcinomas of the larynx are common and require multidisciplinary perioperative management with particularly excellent communication between the surgeon and anaesthesiologist. Early preoperative assessment allows for optimisation, prehabilitation and advanced imaging in cases who present without respiratory compromise. On arrival for surgery, thorough airway examination including preoperative endoscopic airway assessment under topical anaesthesia and airway ultrasound will inform planning for airway management.
Source: Operative Techniques in Otolaryngology - Head and Neck Surgery - Category: ENT & OMF Authors: Source Type: research

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Series Type : Non-coding RNA profiling by array ; Expression profiling by arrayOrganism : Homo sapiens ; synthetic constructThis SuperSeries is composed of the SubSeries listed below.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by array Expression profiling by array Homo sapiens synthetic construct Source Type: research
Contributors : Ming Liu ; Rui ZhaoSeries Type : Expression profiling by array ; Non-coding RNA profiling by arrayOrganism : Homo sapiensWe explored the whole expression profiles of transcriptome included miRNA, circRNA, lncRNA and mRNA in 5 pairs of LSCC and matched non-LSCC tissues by microarrayThe LSCC-related competing endogenous RNA (ceRNA) networks were constructed based on these microarray data.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Non-coding RNA profiling by array Homo sapiens Source Type: research
Contributors : Ming Liu ; Rui ZhaoSeries Type : Non-coding RNA profiling by arrayOrganism : Homo sapiensWe explored the whole expression profiles of transcriptome included miRNA, circRNA, lncRNA and mRNA in 5 pairs of LSCC and matched non-LSCC tissues by microarrayThe LSCC-related competing endogenous RNA (ceRNA) networks were constructed based on these microarray data.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by array Homo sapiens Source Type: research
Contributors : Ming Liu ; Rui ZhaoSeries Type : Non-coding RNA profiling by arrayOrganism : Homo sapiens ; synthetic constructWe explored the whole expression profiles of transcriptome included miRNA, circRNA, lncRNA and mRNA in 5 pairs of LSCC and matched non-LSCC tissues by microarrayThe LSCC-related competing endogenous RNA (ceRNA) networks were constructed based on these microarray data.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by array Homo sapiens synthetic construct Source Type: research
Source: Indian Journal of Surgical Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSIONS: The present work demonstrated that the knockdown of FOXM1 suppressed the proliferation, invasion, and migration of LC cells by the AKT signaling pathway. PMID: 32633370 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
In conclusion, upregulating expression of IL24 may enhance the occurrence of LSCC, which owns prospect diagnostic ability and therapeutic significance in LSCC. PMID: 32623386 [PubMed - as supplied by publisher]
Source: Cancer Biomarkers - Category: Cancer & Oncology Tags: Cancer Biomark Source Type: research
Conclusion and significance: Incidence of thyroid gland invasion in squamous cell carcinoma larynx is low, allowing us not to address thyroid routinely in patients undergoing total laryngectomy for laryngeal carcinoma. PMID: 32633590 [PubMed - as supplied by publisher]
Source: Acta Oto-Laryngologica - Category: ENT & OMF Authors: Tags: Acta Otolaryngol Source Type: research
In this study, we aimed at investigating the expression profiles of ATP-binding cassette (ABC) transporters and stem cell markers in 5-fluorouracil (5-FU) resistant laryngeal Hep-2 cells. We treated parental Hep-2 cells, with stepwise increased doses of 5-FU for almost 1 year to develop 5-FU resistant sub-lines with resistance against varying levels of 5-FU concentrations (4 sub-lines resistant to 1, 2, 4, and eightfold of 5-FU). Then, we measured the expression levels of 10 genes from ABC transporters family and 4 stem cell associated markers using quantitative reverse transcription polymerase chain reaction (qRT-PCR...
Source: Molecular Biology Reports - Category: Molecular Biology Authors: Tags: Mol Biol Rep Source Type: research
ConclusionThe reported experience shows that, in selected cases, it is possible to radically remove lateral hypopharyngeal cancer with acceptable functional results.
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
More News: Airway Management | Anesthesia | Anesthesiology | Cancer & Oncology | Carcinoma | ENT & OMF | Laryngeal Cancer | Respiratory Medicine | Ultrasound