Girls with premature thelarche younger than 3 years of age might have stimulated LH greater than 10 IU/L.

CONCLUSION: Although consensus statements usually define baseline LH >0.3-0.5 IU/L, peak LH >5 IU/L, and LH/FSH ratios >0.66-1.0 as diagnostic cut-offs for CPP, in children below 3 years of age, the baseline and peak LH values may be detected pubertal, possibly due to mini-puberty. The dominant FSH response in the GnRH stimulation test is more valuable than the peak LH response in the diagnosis of PT. PMID: 32349465 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research