Minor temperature shifts do not affect chromosomal ploidy but cause transcriptomic changes in Leishmania braziliensis promastigotes in vitro.
CONCLUSIONS: This study provides evidence that L. braziliensis promastigotes exhibit a decrease in cell density, and noticeable changes in the transcriptomic profiles. However, there were not perceptible changes at chromosome CNVs and only ~3% of the genes changed their copies in each treatment.
PMID: 32348407 [PubMed - in process]
Source: Memorias do Instituto Oswaldo Cruz - Category: Infectious Diseases Authors: Ballesteros N, Vásquez NM, Patiño LH, Cruz-Saavedra L, Ramírez JD Tags: Mem Inst Oswaldo Cruz Source Type: research
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