A Case Report: Rapid Micro-Induction of Buprenorphine/Naloxone to Administer Buprenorphine Extended-Release in an Adolescent With Severe Opioid Use Disorder.

CONCLUSIONS: A rapid sublingual buprenorphine/naloxone micro-induction was successfully used to initiate BUP-XR, thereby eliminating the abstinence period prior to buprenorphine/naloxone administration, shortening the induction period, and minimizing withdrawal. SCIENTIFIC SIGNIFICANCE: This is the first reported case of using rapid micro-induction as a bridge to initiate BUP-XR. By reducing the length of induction to 4 days and minimizing withdrawal, this induction method can make BUP-XR more accessible to patients who would otherwise refuse the medication due to concerns of enduring withdrawal. (Am J Addict 2020;00:00-00). PMID: 32346944 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32346944?dopt=Abstract

Source: The American Journal on Addictions - April 28, 2020 Category: Addiction Authors: Azar P, Wong JSH, Jassemi S, Moore E, Vo DX, Nikoo M, Young S Tags: Am J Addict Source Type: research