Heightened Tamoxifen Activation Masquerading as a Venlafaxine-Associated Adverse Event after Rotation from Duloxetine

Palliative care providers are consulted frequently to manage complex symptoms in medically complex patients. Supportive care of patients with hormone-receptor positive breast cancer often involves consideration of ongoing medical therapy such as tamoxifen. Tamoxifen is an estrogen-receptor modulator with known association with mood disturbances, hot flashes, and fatigue. As palliative care providers, we must be aware of how to optimally manage these challenging symptoms while avoiding drug-drug interactions that could negatively impact the disease prognosis.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Tags: Letter Source Type: research