A new strategy to trigger ferroptosis in target cancer cells using drug-metal coordination complexes

(University of Science and Technology of China) Doxorubicin and ferrous ions could form acid-dissociable coordination complexes, which were incorporated into functionally tailored amorphous calcium carbonate nanoparticles and may confer severe ferroptotic damage to target tumor cells, published on Science Advances.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news