Blockade of Pan-fibroblast Growth Factor Receptors Mediates Bidirectional Effects in Lung Fibrosis.

Conclusions] These data suggest that the total inhibition of FGFR signaling can suppress lung fibrosis by inhibiting fibroblast activities, although alveolar injury is simultaneously caused.
PMID: 32338990 [PubMed - as supplied by publisher]

Source: American Journal of Respiratory Cell and Molecular Biology - April 26, 2020 Category: Molecular Biology Authors: Morizumi S, Sato S, Koyama K, Okazaki H, Chen Y, Goto H, Kagawa K, Ogawa H, Nishimura H, Kawano H, Toyoda Y, Uehara H, Nishioka Y Tags: Am J Respir Cell Mol Biol Source Type: research