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Is Antibacterial Soap Safe? Do We Need It?

I reported back in May that the FDA was going to take a closer look at triclosan, one of the more common ingredients in antibacterial soaps, body washes, and toothpaste. But while triclosan does provide a benefit in toothpaste, helping to prevent gingivitis, the FDA states that it "does not have evidence that triclosan added to antibacterial soaps and body washes provides extra health benefits over soap and water." And since there are some concerns about triclosan, as animal studies show that it can alter hormone regulation (endocrine disruptor) and that it may help make bacteria resistant to antibiotics, the "FDA believes that there should be clearly demonstrated benefits to balance any potential risks."...Read Full Post
Source: About.com Pediatrics - Category: Pediatrics Source Type: news

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This is a systematic review of clinical and laboratory studies evaluating the effect of Melaleuca alternifolia on periodontopathogens, dental plaque, gingivitis, periodontitis, and inflammatory responses. The PubMed, Cochrane, Web of science, Bireme, Lilacs, Prospero, Open Grey, and Clinical Trials databases were searched to identify potentially eligible studies through October 2016. Of 1,654 potentially eligible studies, 25 were included in the systematic review. Their methodology was evaluated through the Cochrane Handbook for clinical studies and the GRADE system for in vivo/in vitro studies. Although clinical studies m...
Source: Phytotherapy Research - Category: Biochemistry Authors: Tags: REVIEW Source Type: research
Aim: Assessment of dental health in the primary dentition of preterm infants (PTI) including investigation of mother- and infant-related risk factors in a case-control study design.Material and Methods: One hundred twenty-eight infants aged 3-4 years were included. Sixty-four PTI (27 males) were randomly selected from the preterm registry of the Jena University Hospital. As a control group served 64 full-term infants (FTI) recruited from the Department of Paediatric Dentistry, matched for age and sex. Dental examinations were provided by one dentist under standard clinical conditions. Caries was scored using the Internatio...
Source: Caries Research - Category: Dentistry Source Type: research
CONCLUSION: Although the commercial product containing essential oils with ethyl lauroyl arginate performed statistically significantly better regarding average plaque scores on all surfaces combined than the placebo (p = .018) and negative control (p = .003) when no mechanical tooth cleaning was performed, the product still left the patient with enough plaque to cause gingivitis and thus seemed of questionable clinical benefit to the patient. ClinicalTrials.gov Identifier is NCT02884817. PMID: 29216779 [PubMed - as supplied by publisher]
Source: Acta Odontologica Scandinavica - Category: Dentistry Authors: Tags: Acta Odontol Scand Source Type: research
Authors: Lopez MA, Manzulli N, D'Angelo A, Lauritano D, Papalia R, Candotto V Abstract It is well known in dentistry that there are numerous chronic conditions that require ongoing and constant management over time, the most noteworthy being periodontal disease, gingivitis and periodontitis. Yet, in recent years, with the increase in the number of implants being placed, mucositis and peri-implantitis have become more and more prevalent pathologies. The results of the statistical analysis demonstrate that there was a slight difference between the pocket depth as measured in the treated sites at time 0 (pre-treatment...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
Authors: Lopez MA, Manzulli N, D'Angelo A, Candotto V, Casale M, Lauritano D Abstract Recently, a specifically designed device was proposed that is able to nebulize particles with a diameter of approximately 16 micrometres to be used mainly in the management of diseases of the upper airway respiratory tract. The purpose of this pilot study is to evaluate the potential efficacy of nebulized hyaluronic acid in the management of gingivitis. The results of the statistical analysis demonstrate that there was no difference between the pocket depth as measured in the treated sites at time 0 (pre-treatment) and time 1 (15 ...
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research
Background: Macrophage migration inhibitory factor (MIF) is a key proinflammatory mediator. Itplays a vital role in immune response against the oral disease. MIF is a regulator of innate immunity, andbacterial antigens can stimulate serum level of this protein. In experimental gingivitis, the expression levelof MIF increases and this increment positively correlates with oral plaque index. The single nucleotidepolymorphisms in the gene encoding the MIF protein can control the function of MIF. The aim of thepresent study was a clarification of the associations between MIF ‑173 G/C, MIF 95 bp, and 189 bpinsertion/deletion (...
Source: Dental Research Journal - Category: Dentistry Source Type: research
We present the case of a rarely seen mucosal pathology, previously referred to in the literature as “plasma cell gingivitis”, in an otherwise fit and healthy Caucasian 23-year-old male. This condition was thought to be associated with historical components of toothpaste or chewing gum, and, was thought to be no longer existent with removal of the causative ingredient from these products. Howev er, we would like to highlight that this entity is still present today and colleagues in our specialty can come across these cases being referred for surgical excision.
Source: The British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: P245 Source Type: research
This study evaluated, in periodontally diseased patients, the effects of a pre-procedural mouth rinse on induced bacteremia. Material and Methods: Systemically healthy individuals with gingivitis (n=27) or periodontitis (n = 27) were randomly allocated through a sealed envelope system to: 0.12% chlorhexidine pre-procedural rinse (13 gingivitis and 13 periodontitis patients) or no rinse before dental scaling (14 gingivitis and 15 periodontitis patients). Periodontal probing depth, clinical attachment level, plaque, and gingival indices were measured and subgingival samples were collected. Blood samples were collected before...
Source: Journal of Applied Oral Science - Category: Dentistry Source Type: research
Oral direct-acting antivirals comprise the main therapy for hepatitis C virus (HCV)-associated liver disease in Japan. Daclatasvir/asunaprevir is the primary agent and sofosbuvir/ledipasvir is the secondary agent for HCV genotype 1b. Ombitasvir/paritaprevir/ritonavir was also recommended as a therapy for HCV genotype 1b. More recently, elbasvir (NS5A inhibitor)/grazoprevir (NS3/4A protease inhibitor) was also recommended as a potent therapy for HCV genotype 1b infection. This agent achieved an SVR12 as high as 96.5% for HCV virus-associated chronic hepatitis. We recently encountered a case treated with this agent and the f...
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
Here's what we chose for you from NEJM Group today: NEJM Clinical Practice Center: Image in Clinical Medicine: A 42-year-old woman presented to...
Source: Physician's First Watch current issue - Category: Primary Care Source Type: news
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