LncRNA promoted inflammatory response in ischemic heart failure through regulation of miR-455-3p/TRAF6 axis

ConclusionsOur results reveal that SOX2-OT may be a driver of IHF through repression of miR-455-3p, and miR-455-3p alleviates IHF by targeting TRAF6. Therefore, SOX2-OT/miR-455-3p/TRAF6 may be a potential target for advanced therapeutic strategy for IHF.
Source: Inflammation Research - Category: Research Source Type: research