Development and validation of next generation sequencing based 35-gene hereditary cancer panel
ConclusionsThe use of targeted NGS-based multigene testing panels to provide comprehensive analysis of cancer susceptible genes has been considered a viable option. In the present study, we developed and validated a 35-gene panel for testing 8 common cancers using next-generation sequencing (NGS). The performance of our hereditary cancer panel is assessed across a board range of variants in the 35 genes to support clinical use.
Source: Hereditary Cancer in Clinical Practice - Category: Cancer & Oncology Source Type: research
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