Risk factors for insulin resistance in midlife Singaporean women

Insulin resistance, diabetes and their attendant complications have reached epidemic proportions in Asian countries. [1,2]. The precursor condition for diabetes is insulin resistance, and up to 20% of Singaporean women have increased insulin resistance, as measured by HOMA-IR; the lifetime risk is more than 50%. [3] Further, insulin resistance and type 2 diabetes develop at a younger age and at a lower body mass index in the Asian population than in Western populations. [1,2] Obesogenic diets and physical inactivity, leading to central obesity and lower muscle mass, are believed to underlie the higher prevalence of insulin resistance and diabetes in Asians.[1,2]

Source: Maturitas - April 26, 2020 Category: Primary Care Authors: Inger Sundstr öm-Poromaa, Win Pa Pa Thu, Michael S. Kramer, Susan Logan, Jane A. Cauley, Eu-Leong Yong Source Type: research