Montelukast Has no Impact on the Systemic Production of TGF β-1 in Patients with Nasal Polyposis Associated with Aspirin Intolerance

Conclusion we found no impact of the therapy with a leukotriene receptor blocker on the production of TGF-β1, making the antileukotriene therapy a highly questionable choice for the treatment of nasal polyposis, particularly from the standpoint of seeking to modify the remodeling process in this disease. [...] Thieme Revinter Publicações Ltda Rio de Janeiro, BrazilArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text

Source: International Archives of Otorhinolaryngology - April 26, 2020 Category: ENT & OMF Authors: Pezato, Rog ério Greg ório, Luciano Lobato P érez-Novo, Claudina Bezerra, Thiago Ferreira Pinto Kosugi, Eduardo Macoto Tags: Original Research Source Type: research