Effects of red blood cell concentrate transfusion on blood tacrolimus concentration

Conclusion Change in the blood concentration/dose ratio of tacrolimus was associated with change in the hematocrit ratio after transfusion, and more attention is required for children or patients with small body surface area. Dose adjustment of tacrolimus is required if the blood concentration of tacrolimus is much higher than the target concentration.
Source: International Journal of Clinical Pharmacy - Category: Drugs & Pharmacology Source Type: research