Decreased brain and muscle ARNT-like protein 1 expression mediated the contribution of hyperandrogenism to insulin resistance in polycystic ovary syndrome.

CONCLUSIONS: Decreased BMAL1 expression in the liver and adipose played a potentially novel role in the contribution of hyperandrogenism to insulin resistance, which might be a possible mechanism accounting for the pathogenesis of PCOS. PMID: 32334629 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32334629?dopt=Abstract

Source: Reproductive Biology - April 24, 2020 Category: Reproduction Medicine Authors: Zhai J, Li S, Hu M, Di F, Liu J, Du Y Tags: Reprod Biol Endocrinol Source Type: research