Study finds no overall survival benefit, but improved quality of life with talazoparib in advanced BRCA-mutated breast cancer

(University of Texas M. D. Anderson Cancer Center) New data from the Phase III EMBRACA trial led by researchers at The University of Texas MD Anderson Cancer Center found the PARP inhibitor talazoparib did not demonstrate a statistically significant overall survival (OS) benefit for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes. Most patients included in the study went on to receive subsequent systemic therapies, which may have affected the survival outcome analysis.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news